DI2-ETHYLHEXYL PHTHALATE reacts with acids to liberate heat along with alcohols and acids. Di2-EthylhexylPhthalate DEHP Draft for Public Comment December 2019.
Major Di 2 Ethylhexyl Phthalate Dehp Metabolic Pathways And Download Scientific Diagram
DEHP is also called bis2-ethylhexyl phthalate or dioctyl phthalate DOP.
Di 2 ethylhexyl phthalate. 5 F-gases subject to emission limitsreporting per Regulation 5172014EU. The di 2-ethylhexyl phthalate DEHP is a plasticizer incorporated to plastic matrices of widely used consumer products. 2 the Candidate List of SVHCs.
Although DEHP similar to other members of the phthalates family is generally considered as an endocrine disruptor the. Di2-ethylhexyl phthalate DEHP CAS No. Test atmospheres of the phthalates were generated.
DEHP is the most commonly used plasticizer that makes plastic more flexible and elastic. It has been reported that approximately 4050 of the global annual PAEs production is DEHP Zhao et al 2016. Patients can be additionally exposed through DEHP-containing medical devices.
1 Table 3 of Annex VI to CLP. Nevertheless DEHP-induced hepatotoxicity at the molecular level in quail remains unexplored. Methods S33 dibutyl phthalate 3 and S40 di2-ethylhexyl phthalate 4 were issued on January 17 1975 and validated over the range 2 to 10 mgm3 at 23 and 25 C and 767 mm and 761 mm Hg respectively using 30- and 32-L air samples 12.
It is colorless viscous and soluble in lipophilic liquid. Di2-ethylhexylphthalate DEHP is a reproductive and developmental toxicant in animals and a suspected endocrine modulator in humans. DI2-ETHYLHEXYLPHTHALATE ii DRAFT FOR PUBLIC COMMENT DISCLAIMER Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic.
Di-2-ethylhexyl phthalate DEHP is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Di- 2-ethylhexyl phthalate DEHP is a widespread environmental toxicant that severely impacts agricultural production and animal and human health. Since that time new data have become available and these have been incorporated into the Monograph and taken into.
In 2011 Taiwan authorities reported that two phthalates including di- 2-ethylhexyl phthalate and di-iso-nonyl phthalate were intentionally introduced into a variety of foods and beverages during the course of 15 years. Phthalic acid bis2-ethylhexyl DI2-ETHYLHEXYL PHTHALATE This substance was considered by previous Working Groups in October 1981 IARC 1982 March 1987 IARC 1987 and February 2000 IARC 2000. Di2-ethylhexyl phthalate was tested in mice and rats by oral administration.
Di2-ethylhexyl phthalate DEHP as representative plasticizer is one of the most abundantly used and ubiquitous phthalic acid esters PAEs in industry. Di2-ethylhexylphthalate DEHP Why am I being warned about potential exposure to DEHP. Di-2-ethylhexyl phthalate DEHP is the most common member of the class of phthalates which are used as plasticizers in polymer products to make plastic flexible.
There is widespread exposure to DEHP in the general population. And 6 volatile organic compounds VOCs listed in the Ambient Air Directive 200850EC. However it is gradually released from these products resulting in a chronic exposure for humans.
Di2-ethylhexyl phthalate can cause testicular damage in rats. DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. 4 Annex XVII of REACH Restrictions List.
DEHP-3456-d4 Deuterated DEHP Deuterated bis 2-ethylhexylphthalate Dioctyl phthalate-3456-d4 Phthalic acid-3456-d4 bis 2-ethylhexyl ester Empirical Formula Hill Notation. This list contains a non-exhaustive inventory of substances taken from. 117-81-7 is the diester of phthalic acid PA and the branched-chain 2-ethyl-1-hexanol 2-EH.
Many studies have shown that DEHP causes testicular toxicity through oxidative stress but the specific mechanism is unknown. It is hypothesized that the teratogen di2-ethylhexyl phthalate DEHP acts by in vivo hydrolysis to 2-ethylhexanol 2-EXHO which in turn is metabolized to 2-ethylhexanoic acid 2-EXHA the proximate teratogen. Teratological studies were conducted with Wistar rats with administration of these agents on day 12 of geatation.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. 3 Annex XIV of REACH Authorisation List. Heat is also generated by the interaction of esters with caustic solutions.
However little is known ab. It significantly increased the incidence of benign and malignant liver-cell tumours in animals of both species and a dose-response relationship was observed.
