Thursday, June 28, 2018

Blood Sugar Measurement

Ear lobe finger web and finger cuticle skin of the forearm lip mucosa oral mucosa tongue nasal septum cheek arm Limitations The weak glucose spectral bands not only overlap with the stronger bands of water but also of hemoglobin proteins and fats. Healthy Life Time Changes Can Slow Down or Stop the Progression Of Diabetes.

Time In Range A New Blood Sugar Metric For People With Diabetes Stat

A fasting blood glucose reading of 61 mmolL 110 mgdl or less is considered normal.

Blood sugar measurement. Glucose is a sugar that you get from food and drink. Even if you use a CGM youll still need a. While this conversion chart for blood sugar levels is a good guideline everyones body responds differently.

These tell you what your blood sugar level is at the time you test. For people with diabetes blood sugar level targets are as follows. Ad Our Nutritionists Are Working To Prepare Most Appropriate Diabetic Plan For Your Diabetes.

A normal blood sugar is lower than 140 mgdl. 20 rows Conversion Table for Blood Glucose Monitoring People from outside the US may find this. Fasting normal blood sugar Normal for person without diabetes.

Ad Our Nutritionists Are Working To Prepare Most Appropriate Diabetic Plan For Your Diabetes. Mgdl 18 mmoll. The international standard way of measuring blood glucose levels is in terms of a molar concentration measured in mmolL millimoles per litre.

Healthy Life Time Changes Can Slow Down or Stop the Progression Of Diabetes. What is a normal blood sugar level. Blood Sugar - this term describes the amount of glucose in blood.

Your blood sugar levels also known as blood glucose levels are a measurement that show how much glucose you have in your blood. Blood sugar measurement is also typically included in routine lab work for people without diabetes -- your physician will usually order a glycated hemoglobin A1C. The pre-diabetic range is more than 61 mmolL to 69 mmolL 110 mgdl to 125 mgdl.

In the United States and continental Europe mass concentration is predominantly measured in. Blood sugar also called blood glucose needs to be tightly controlled in the human body to minimise the risk of complications developing. Usually described in moles per liter or milligrams per deciliter.

Under 9 mmolL for people with type 1 diabetes and under 85mmolL for people with type 2 diabetes. Or millimolar mM for short. Someone who does not have diabetes is unlikely to be checking their blood sugars.

How do I check my blood sugar. A continuous glucose monitor. Formula to calculate mmoll from mgdl.

4 to 7 mmolL for people with type 1 or type 2 diabetes. Formula to calculate mgdl from mmoll. Blood sugar testing requires the use of a blood sugar meter.

A blood sugar between 140 and 199 mgdl is considered to be prediabetes and a blood sugar of 200 mgdl or higher can indicate diabetes. There are two ways to measure blood sugar. Blood glucose is measured using a kind of confusing system that exists out of our stubbornness to change outdated systems or to keep doctors and scientists in business.

The A1C A-one-C is a test done in a lab or at your providers office. Blood sugar checks that you do yourself. In the USA its measured using milligrams per deciliter mgdl.

Your blood sugar levels go up and down throughout the day and for people living with diabetes these changes are larger and happen more often than in people who dont have diabetes. 7099 mgdl 3955 mmolL Official ADA recommendation for someone with diabetes. Blood sugar levels in diagnosing diabetes.

80130 mgdl 4472 mmolL Normal blood sugar 2 hours after meals. This test tells you your average blood sugar level over the past 2 to 3 months. The answer to the question what is a normal blood sugar level is as follows.

People can measure their blood sugar levels with either a blood sugar meter or a continuous glucose monitor. Too high or too low levels of blood sugar can result in serious health problems. The standard level of blood sugar in humans is around 45-55 molesliter.

The meter measures the amount of sugar in a small sample of blood usually from your fingertip that you place on a disposable test strip. Mmoll mgdl 18. In the UK and commonwealth countries its measured using millimoles per liter mmolL.

Wednesday, June 27, 2018

Cchd Newborn Screening

Screening is Important Pulse oximetry is a quick and painless test to measure the level of oxygen in a babys blood. Newborn CCHD screening uses a device called a pulse oximeter to measure oxygen in the babys blood.

Plos One Development Of A Newborn Screening Program For Critical Congenital Heart Disease Cchd In Taipei

Newborn screening for critical congenital heart defects Critical CHDs can identify newborns with these conditions before signs or symptoms are evident and before the newborns are discharged from the birth hospital.

Cchd newborn screening. Seven years after its addition to the US Recommended Uniform Screening Panel newborn screening for critical congenital heart disease CCHD using pulse oximetry became mandatory in the United States. Newborn screening for CCHDs involves a simple bedside test called pulse oximetry. The panel decided the current recommended screening window between 24 and 48 hours after birth would remain the same given the increase in false positives when screening is completed too early.

If detected early infants affected with CCHD can often be. Global Newborn Screening Market By Test Type Dried Blood Spot Test Hearing Screen Test Critical Congenital Heart Diseases CCHD Test Global Newborn Screening Market By Product Type Instruments Reagents and Assay Kits. Nursing theories and ethical principles serve as the foundation of nursing practice education and research Colley 2003.

Newborn screening for critical CHDs involves a simple bedside test called pulse oximetry. Although CCHD newborn screening reduces morbidity and mortality there remain important opportunities to. After birth newborn CCHD screening usually happens when a baby is between 24 and 48 hours ol d.

Unlike blood-spot screening for metabolic conditions CCHD screening is a point-of-care test. Pulse oximetry screening for Critical Congenital Heart Disease CCHD is now available for babies in Ontario. CCHD refers to conditions where a babys heart or major blood vessels around the heart have not formed properly.

This means that the screening should be universal for all newborns. The 28-page report recommends that newborn screening be done with motion-tolerant pulse oximeters that. A low level of oxygen can be a sign that a baby has CCHD.

Newborns and Children SACHDNC acted on the HHS 2010 recommendation and outlined a strategy for routine screening of newborns to improve detection of CCHD. Continue screening between 24 to 48 hours after birth. Newborn Screening The process of testing for disease in a person who does not show signs of having the disease nonsymptomatic or asymptomatic person.

Low levels of oxygen in the blood can be a sign of a CCHD. This papers purpose is to elaborate on the authors discussion of her phenomenon of interest POI on newborn screening for Critical Congenital Heart Defects CCHD. This test estimates the amount of oxygen in a babys blood.

4715 These five studies represent a total of 241239 infants and include the largest CCHD screening study to date with over 122738 subjects. Since then CCHD screening has become nearly universal in the United States. Congenital heart disease CCHD is the most common birth defect.

A positive screen does not mean that your baby has CCHD but that further evaluation is needed to. Screening for the most critical forms CCHD using pulse oximetry was added to the Recommended Uniform Screening Panel in the United States in 2011. Critical CHD Screening Methods.

Oxygen is important for the body to function. To get a comprehensive overview of the Newborn Screening market. Pulse oximetry newborn screening is a non-invasive test that measures how much oxygen is in the blood and can help to identify babies that may be affected with CCHD before they leave the newborn nursery.

FOR CRITICAL CONGENITAL HEART DISEASE CCHD. They need more tests to diagnose the condition. The test is done using a machine called a pulse oximeter with.

This means that all of the screening happens within the hospital. Newborns with low blood oxygen are at higher risk for CCHD. To date there have been five published CCHD screening studies that exclusively used Masimo SET pulse oximeters and sensors 4513-15 two of which 59876 subjects were the basis for the CCHD workgroup recommendation for CCHD screening protocols.

Through a collaborative quality improvement project between the cardiology department at Childrens Healthcare of Atlanta CHOA and the neonatology department at Northside Hospital a retrospective review was conducted on newborn CCHD screening results collected on term infants born between January 1 2013 and December 31 2016 at Northside Hospital a large tertiary birth hospital. Newborn screening for CCHD is done by measuring the oxygen levels in your babys body. Low levels of oxygen in the blood can be a sign of a critical CHD.

The goal of screening is to catch the disease in its early stages. During screening a special piece of equipment called a pulse oximeter measures how much oxygen is in your babys blood. It is recommended that the newborn be screened for CCHD utilizing the pulse oximetry algorithm at 24-48 hours even if on supplemental oxygen.

This test estimates the amount of oxygen in a babys blood. To learn more about this process visit the Pulse Oximetry Screening page. The test is done using a machine called a pulse oximeter with sensors placed on the babys right hand and one foot either right or left.

CCHD Screening 782 Words 4 Pages. SegementationGlobal Newborn Screening Market. CCHD screening is a component of newborn screening.

Humidifier Mold Prevention

Even worse it will continue to grow until steps are taken to eliminate the source of moisture and effectively deal with the mold problem. In my opinion additives such as white vinegar work best and can be put safely into the humidifier water to prevent mold.

Solved How To Prevent Mold In A Humidifier

It easily kills mold spores and doesnt cause any harm or damage to the components of your humidifier.

Humidifier mold prevention. For starters the humidifier should be placed at least 12 inches away from the ground or surrounding walls of the room. A cup of white vinegar while filling the tank. Then refer to the.

Humidifier tablets that are designed to. The spread of Aspergillus mold in hospital rooms is now linked to a hospital humidifier that was not turned on for more than a decade. Heres how you can do it.

Keep your humidifier clean to prevent mold from reoccurring. The humidifier had not been used for a decade. If you put the humidifier too close to a wall you run the risk of developing a mold infection inside it.

Use distilled water not tap water. The Centers for Disease Control and Prevention CDC said that a humidifier is the cause of a deadly cause of Aspergillus mold infections at Seattle Childrens. White vinegar one of the easiest ways to clean the tank is by using white vinegar which will kill bacteria and mold.

One of the least expensive options for preventing mold in the humidifier hydrogen peroxide kills bacteria and mold. Humidifiers create extra moisture in the air and can encourage the growth of mold and mildew. Just a few drops into the water reservoir will get the job done.

First thing first unplug your humidifier before proceeding with the cleaning. When you fill your humidifier simply adding a cup of white vinegar to the well will help prevent mold from growing. Clean every two to three days.

One cup added to your humidifiers water reservoir will work correctly. Mix two cups of vinegar with one cup of water and pour this into the empty tank. Being a natural antimicrobial it will destroy any mold that it comes across and also prevent any further growth.

Adding a cup of white vinegar to the tank when you fill your humidifier will help prevent mold from growing. The CDC finds humidifier is the cause of deadly mold contamination at Seattle Childrens Hospital. Every third day of use unplug the humidifier and soak the reservoir in a 10 percent bleach solution for.

Vinegar is a natural antibacterial antimicrobial and will not harm the various parts of the humidifier while it kills mold spores. Also you can buy humidifier tablets to drop in and its the same effect for a higher price. Preventing mold in a humidifier also requires proper disinfecting.

Vinegar is a natural antimicrobial and antibacterial product that will not harm the various parts of the humidifier while it kills mold spores that it comes in contact with. An anti-microbial as well as antibacterial white vinegar is excellent for preventing mold. Additionally make sure that theres nothing placed above the humidifier.

If the water bucket is full empty out the remaining water in the reservoir. Use the diagram above to assess the extent of mold in your home. Here are some tips to minimize the risk of mold and bacteria accumulating in and around your humidifier.

Here is everything you can add to prevent mold growth in a humidifier. By adding a cup of white vinegar you will be able to prevent the growth of mold inside your humidifier. Add one cup of white vinegar to the water in your humidifier to prevent mold growth.

Many people recommend products like tea tree essential oils hydrogen peroxide Lysol etc. Then the humidifier was switched on in. High humidity steam cooking dryer vents humidifiers Mold and mildew will develop within 24-48 hours of water exposure.

Apply a few drops of 3 percent hydrogen peroxide or white distilled vinegar and mix it up with water. Wear rubber gloves to avoid direct contact with mold. Amazons Choice for Humidifier Mold Prevention Guardian Technologies GGHS15 Aquastick Antimicrobial Humidifier Treatment 2-Pack Pure Guardian Humidifiers Evaporative Humidifier Water Tanks 44 out of 5 stars 5798.

Replace the water and rinse out the tank daily.

Flu In My Area

Flu Vaccines in Your Area. Cold and Flu Activity Map and News WeatherBug.

Rapid Test Terhadap Infeksi Dan Strategi Menghadapi Wabah Virus Flu

Live Attenuated Influenza Vaccine LAIVNasal Spray Vaccine.

Flu in my area. The finder allows you to search for locations near you that have the flu shot available. Weekly national flu reports. Here a list of places including Walgreens CVS Target and Walmart where you can get your flu shot for free withand sometimes withoutinsurance.

All adult flu vaccines are given by injection into the muscle of the upper arm. Froedtert Pharmacy locations allow walk-in flu and pneumonia shots. Data collected in ILINet are used to produce a measure of ILI influenza like illness activity by state.

Advancements in Influenza Vaccines. Call ahead to see if your insurance is accepted. Flu Vaccination by Jet Injector.

It can take 10 to 14 days for the flu vaccine to work. National influenza reports tracking seasonal flu and other seasonal respiratory illnesses in the UK. How Flu Vaccines are made plus icon.

Prepare yourself know the symptoms and feel better. Flu vaccine side effects. Use our flu vaccination checker to find out if youre eligible for a free flu vaccination and where.

Are colds and flus in your neighborhood. 2019 to 2020 season - GOVUK Cookies on GOVUK. Doctors speculate that coronavirus precautions might be helping.

Join 60000 Flu Trackers across the nation in monitoring the flu. Enter your ZIP code or click on the map to get started. You do NOT have to have an established primary care provider or be an existing Froedtert MCW patient to receive the vaccine with the pharmacies.

Influenza is spread by contact with respiratory droplets when an infected person coughs or sneezes. Keep in mind that while the tool can be helpful its search results arent all-inclusive. How to get the flu vaccine in your area.

It can cause severe illness and life-threatening complications. Different Flu Vaccines plus icon. Everyday Health Flu Map Tracker.

Cold and Flu Conditions in Your Area. State Activity Indicator Map. Your Primary Care Physician May Offer Free Flu Shots.

Flu vaccines are very safe. Twelve disease categories are used to help you quickly find what youre looking for within your local area. Outbreaks Near Me Sign up for email alerts COVID-19 Outbreak News COVID-19 Case Counts United States Flu Trends.

Influenza flu is a contagious illness of the respiratory tract caused by influenza viruses. Having the flu vaccine will also stop you spreading flu to other people who may be more at risk of serious problems from flu. Please note there are no vaccinations at the Mequon location.

For more than 20 years Earth Networks has operated the worlds largest and most comprehensive weather observation lightning. Skip to main content. On your first visit to the site you can register by entering your sex date of birth zip code and an email address.

All you need is a smartphone computer tablet or any other device to register either via the website mobile app or Facebook. This series of dynamic visualizations allow any Internet user to access influenza information collected by CDCs monitoring systems. Look up your local health department here to see if free flu shots are available in your area.

Influenza surveillance data the way you want it. Centers for Disease Control and Prevention reports seasonal influenza activity remains lower than usual for this time of year. Most of the categories refer to where the disease affects your body such as Gastrointestinal for.

Flu shots are billed by the retail pharmacy to your pharmacy insurance. Use our map to follow flu-risk trends and predictions in your area. Depending on your insurance plan occupation.

As of October 1 2020 Yolo County is hosting free flu vaccination clinics to help all residents and families Fight the Flu.

Tuesday, June 26, 2018

Ellis County Health Department

Tmnstaff January 21 2021 No Comments COVID-19 ellis county Ellis County Commission Ellis County Health Department jason kennedy Justin Sabata KDHE BY JUSTIN SABATA As the pandemic approaches another month on the calendar the situation has improved in Ellis County. The Ellis County Health Department on Friday reported the average number of new coronavirus cases per day in the last seven days rose from one on Wednesday to two on Friday.

Ellis County Health Department Home Facebook

United States Phone Number.

Ellis county health department. ELLIS COUNTY Kan. From the start weve told. The Health Department provides immunizations for adults and children WIC program lab testing blood pressures etc.

Ellis County Health Department Organization Address. The Health Department provides immunizations for adults and children WIC program lab testing blood pressures etc. The Ellis County Health Department is open Monday through Thursday between the hours of 700 am.

Ellis County Health Department. Public Health DepartmentSocial Services Department Governmental Audiences. BY JUSTIN SABATA.

Ellis County will move to Phase 3 and 4 of the states vaccination plan on Monday 3222021. The Ellis County Health Department is open Monday through Thursday between the hours of 700 am. KWCH - Starting Oct.

Ellis County Health Department COVID Update. KSNW The Ellis County Health Department has been made aware of a scam involving the COVID-19 vaccine. HAYS Kan-Ellis County Health Department is currently monitoring a rise in the number of COVID-19 cases in our county.

2188 likes 64 talking about this. The risk in Ellis County will decrease to medium risk if the daily case rate drops to less than about 28 cases per 100000 people over the past two weeks and the test positivity stays low. The following statistics were reported by the Ellis County Health Department via their online COVID-19 PortalEllis County residents have been encouraged by the ECHD to use the portal for the most local and up-to-date information regarding the ongoing pandemic.

Ellis County Health Department. The Ellis County Health Department located in Hays KS monitors public health risks coordinates Hays agencies responding to public health threats and enforces Kansas public health standards. To set up an appointment call 785 628-9440.

785 628-9440 Main 785 628-0804 Domestic Fax. The Health Department provides immunizations for adults and children WIC program lab testing blood pressures etc. The office is closed each day between Noon and 100 pm.

1 the Ellis County Health Department will offer flu shots to residents. Ellis County Health Department. HaysMed part of The University of Kansas Health System will host the annual HaysMed Drive-Thru Flu.

Ellis County Health Department. 2175 likes 36 talking about this. HaysMed part of The University of Kansas Health System will host the annual HaysMed Drive-Thru Flu Shot clinic on Sunday September 27.

Ellis County Health Department. Ellis County Health Department. Due to the change.

As a Department of Public Health DPH the department works to prevent the spread of diseases promote healthy behaviors and ensure a clean water supply. Several people who have recently tested positive for COVID-19 attended house parties and visited bars in Hays on Friday 8142020 and Saturday 8152020. Home Search Results Ellis County Health Department.

2178 likes 35 talking about this. 785 628-9440 Main 785 628-0804 Domestic Fax Website. The Ellis County Health Department has information on its website and Facebook page for those tested in the parking lot to get their test results from the company.

The office is closed each day between Noon and 100 pm. Ellis County Health Department director Jason Kennedy said Friday he is still waiting to hear results on the third person who was tested Thursday evening.

Monday, June 25, 2018

What To Do When Pregnant

Call your doctor if you have nausea loss of appetite vomiting jaundice or fatigue combined with itching. If youre pregnant you should take precautions to protect yourself from getting COVID-19.

What Happens After You Get A Positive Pregnancy Test

Do everything you can including physical distancing wearing a mask hand-washing and staying in close communication with your provider.

What to do when pregnant. Your doctor minister or rabbi may also be helpful. In this section of womenshealthgov we call all health care professionals doctor only to keep the information as easy to read as possible. Pregnancy might leave you feeling delighted anxious exhilarated and exhausted sometimes all at once.

Its natural to worry about your babys health your adjustment to parenthood and the financial demands of raising a child. If you have discomfort you may have to try new positions. This will be the first appointment that kicks off your pregnancy care antenatal care.

They include obstetricians family physicians midwives and nurse-midwives. Your GP will let the midwifery team know you are pregnant and they. Stay organised throughout your pregnancy You can print the list on this page to keep track of things you need to do during your pregnancy such as book antenatal classes tell your work youre pregnant and think about where youd like to have your baby.

Several types of health care professionals can help pregnant women and deliver babies. The Pregnancy Diet Fitness Pregnancy Nutrients Healthy Eating The Best Foods Foods to Avoid The Best Exercises Exercises to Avoid. Try to find someone who wont pressure you into making a decision you are not comfortable with.

It will help to talk to someone you trust. You can sign up here to get weekly emails from our midwives that track your babys development in the womb tell you what to expect next and let you know what you need to do and when. The health and well-being of.

From what nutrients you need each week to what exercises are safe these will help you eat well and stay fit during your pregnancy. Track your babys development. Even if youre thrilled about being pregnant a new baby adds emotional stress to your life.

Deciding what to do when youre pregnant can be a very difficult choice to make. So make sure youre getting enough folic acid start taking a prenatal vitamin your healthcare provider can recommend one for you eat a healthy pregnancy diet consider a pregnancy-friendly exercise routine and try to get plenty of sleep. Talk with your doctor if you have any questions about the safety of intercourse during your pregnancy.

This can be your babys father a family member or a friend. Most women can continue with their everyday activities during pregnancy and only need to make some minor lifestyle changes. These can be signs of a serious liver problem If you notice any sudden or extreme swelling or if you gain a lot of weight really quickly call your doctor right away.

Saturday, June 23, 2018

Ocrevus Package Insert

Genentech data on file. Primary progressive MS in adults.

Https Www Accessdata Fda Gov Drugsatfda Docs Label 2018 761053s012lbl Pdf

Indicated for adults with relapsing or primary progressive forms of multiple sclerosis.

Ocrevus package insert. Ocrevus 300 mg10 mL single-dose vial. 21 Assessments Prior to First Dose of OCREVUS. OCREVUS ocrelizumab prescribing information.

See full prescribing information for complete boxed warning Renal dysfunction acute renal failure osmotic nephropathy and death may occur with immune globulin intravenous IGIV products in. OCREVUS ocrelizumab injection is a preservative-free sterile clear or slightly opalescent and colorless to pale brown solution supplied as a carton containing one 300 mg10 mL 30 mgmL single-dose vial NDC 50242-150-01. Primary progressive MS in adults.

OCREVUS is a prescription medicine used to treat. Administer all immunizations according to immunization guidelines at least 4 weeks prior to initiation of OCREVUS for live or live-attenuated vaccines and whenever possible at least 2 weeks prior to initiation of OCREVUS for non-live vaccines. 2 DOSAGE AND ADMINISTRATION 21 Assessments Prior to First Dose of OCREVUS.

Ocrevus ocrelizumab injection is a preservative-free sterile clear or slightly opalescent and colorless to pale brown solution supplied as a carton containing one 300 mg10 mL 30 mgmL single-dose vial NDC 50242-150-01. Prior to initiating OCREVUS perform Hepatitis B virus HBV screening. Relapsing forms of multiple sclerosis MS to include clinically isolated syndrome relapsing-remitting disease and active secondary progressive disease in adults.

Do not freeze or shake. OCREVUS is indicated for the treatment of. Hepatitis B Virus Screening.

South San Francisco CA. 300 mg IV once. Repeat dose 2 wk later.

It is not known if OCREVUS is safe and effective in children. Store OCREVUS vials at 2C8C 36F46F in the outer carton to protect from light. Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.

OCREVUS 600 mg two 300 mg infusions two weeks apart every 24 weeks Placebo. Relapsing forms of multiple sclerosis MS to include clinically isolated syndrome relapsing-remitting disease and active secondary progressive disease in adults 1 Primary progressive MS in adults 1 DOSAGE AND ADMINISTRATION. Montalban X Hauser SL Kappos L et al.

OCREVUS is contraindicated in. Administer OCREVUS under the close supervision of an experienced healthcare professional with access to appropriate medical support to manage severe reactions such as serious infusion reactions. Assessment report as adopted by the CHMP with.

N488 N244 Defined as an increase of 10 point or more from the baseline EDSS score for patients with baseline score of 55 or less or an increase of 05 or more when the baseline score is more than 55. It is not known if OCREVUS is safe and effective in children. I have reviewed your drug coverage policy and feel that coverage approval authorization should be covered for Drug name as it is medically necessary to treat the diagnosis of Diagnosis and ICD-10 code.

Ocrevus 300 mg10 mL single-dose vial. Relapsing forms of multiple sclerosis MS to include clinically isolated syndrome relapsing-remitting disease and active secondary progressive disease in adults. Montalban X Hauser SL Kappos L et al.

Store Ocrevus vials at 2C to 8C 36F to 46F in the outer carton to protect from light. Ocrelizumab versus Placebo in Primary. OCREVUS is indicated for the treatment of adult patients with relapsing or primary progressive forms of multiple sclerosis.

N Engl J Med. Primary progressive MS in adults. Relapsing forms of multiple sclerosis MS to include clinically isolated syndrome relapsing-remitting disease and active secondary progressive disease in adults.

South San Francisco CA. This letter of Insert level of appeal appealis in regards to your coverage policy for Drug name. OCREVUS may interfere with the effectiveness of non-live vaccines.

OCREVUS is a prescription medicine used to treat. 2 DOSAGE AND ADMINISTRATION. Do not freeze or shake.

OCREVUS is a CD20-directed cytolytic antibody indicated for the treatment of.

Highlights Seek And Find

Thousands of new high-quality pictures added every day. HIGHLIGHTS KIDS Watch More On YouTube. Birds Of A Feather Highlights Kids Create...